Evidence & Safety
Separate science from hype.
How to evaluate claims, understand safety questions, and tell FDA-approved uses apart from experimental or research-only compounds.
Articles
- The Peptide Evidence Ladder: Proven, Promising, or Hype? — Learn how to evaluate peptide claims using a simple evidence ladder. Understand the difference between animal studies, human trials, FDA-approved peptide drugs, and wellness hype.
- Are Peptides Safe? — An honest look at peptide safety — what is known, what isn't, and the questions to ask before considering them.
- FDA-Approved vs Research Peptides — Learn the difference between FDA-approved peptide medicines, compounded peptides, and research peptides — including safety, evidence, quality, and why some peptides are promising but still unproven.
- Research Use Only Peptides: What That Label Means — What the "research use only" label actually means and why it matters for consumers.
- U.S.-Made vs China-Made Peptides — Why peptide quality depends less on country of origin and more on identity testing, purity, net content, endotoxin, sterility, supply-chain honesty, and batch-specific COAs.
- How to Read a Peptide COA — Learn how to read a peptide Certificate of Analysis, including identity, purity, net content, LC-MS, HPLC, endotoxin testing, sterility, lot numbers, and common red flags.
- FDA 503A Peptide Hearings — The FDA's July 2026 PCAC hearings will review several peptides for possible inclusion on the 503A Bulks List. Learn which peptides are being reviewed, what happens after the hearings, and why prescription availability may take months.
- Pre-Protocol Health Checklist — The essential preparation checklist to complete before your first peptide protocol: baseline bloodwork, health-history screening, realistic goal-setting, injection basics, storage and sourcing, and how to track your response.