GH Optimization Stack
Unlock your body's natural growth hormone production — two peptides that work together to create powerful, sustained GH pulses
Your body already produces growth hormone. The problem is that production declines significantly with age — dropping roughly 14% per decade after 30. The GH Optimization Stack doesn't introduce synthetic growth hormone. Instead, it signals your pituitary gland to produce more of your own.
CJC-1295 (without DAC) is a GHRH analog that tells your pituitary to release growth hormone. Ipamorelin is a selective GHRP that amplifies the signal through a completely different receptor pathway. Used together, they create a synergistic GH pulse that's significantly stronger than either peptide alone — without the side effects associated with direct GH injection.
The result is elevated natural GH levels that improve sleep quality, accelerate recovery, support fat loss, enhance skin quality, and promote lean muscle development. Unlike synthetic HGH, this combination preserves your body's natural feedback loops, producing GH in pulses that mirror your body's natural rhythm rather than flooding your system with a constant, unnatural level.
Component peptides
- CJC-1295 (no DAC) — Sustained GHRH signaling for GH elevation: 100-300 mcg/dose SubQ
- Ipamorelin — Clean, selective GH pulse via ghrelin pathway: 200-300 mcg/dose SubQ
Combined dosing protocol
CJC-1295 + Ipamorelin is typically pre-mixed in a single vial and administered as a single subcutaneous injection. A standard dose is approximately **300-600 mcg of the combined stack** per injection (delivering ~100-300 mcg CJC-1295 + ~200-300 mcg Ipamorelin). Plug the total stack mcg into our dosing calculator along with your vial size and reconstitution volume to get the exact number of syringe units to draw. The most effective timing is before bed on an empty stomach (at least 2 hours after your last meal), as this amplifies the natural GH surge that occurs during deep sleep. Many people also add a morning dose on an empty stomach for enhanced results. Avoid eating, especially carbohydrates, for 30 minutes after injection, as insulin blunts GH release. Standard cycles run 8-12 weeks with a 4-week break.
Notes
Most people notice improved sleep quality within the first week. Body composition and recovery benefits typically become apparent over 4-8 weeks. This is one of the most popular and well-established peptide combinations, often used as a foundation that other peptides are added to.